"Often the great scientists, by turning the problem around a bit, changed a defect to an asset. For example, many scientists when they found they couldn't do a problem finally began to study why not. They then turned it around the other way and said, "But of course, this is what it is" and got an important result."
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Source : "'You and Your Research' - 1986 Speech by Dr. Richard W. Hamming". www.valueinvestingworld.com. September 21, 2009.