"Buddhist epistemologists do argue that rational analysis leads to the conclusion that rational analysis cannot give us infallible access to truth, including that one. That's not self-defeating, though; it only induces an important kind of epistemic humility and a clearer view of what we do when we reason. We engage in one more fallible human activity among many."
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Source : "Buddhist howls". Interview with Richard Marshall, www.3ammagazine.com. December 28, 2012.