"The development of the Vertebrate proceeds from an axis upward, in two layers, which coalesce at the edges, and also downward, in two layers, which likewise coalesce at the edges. Thus two main tubes are formed, one above the other. During the formation of these, the embryo separates into strata, so that the two main tubes are composed of subordinate tubes which enclose each other as fundamental organs, and are capable of developing into all the organs."

-- Karl Ernst von Baer

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